Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study to optimize Selective Laser Trabeculoplasty (SLT) application when used in the management of open angle glaucoma (OAG)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 years and older

• Ability to comprehend the study procedures and agreement to proceed with primary SLT treatment

• Diagnosis of primary or secondary open angle glaucoma or glaucoma suspects with ocular hypertension

• Bilateral disease

• Pre-SLT IOP \>21 mmHg measured at least twice during patient's lifetime with or without medication

• Open angles with moderate to intense trabecular pigmentation

• Mild to moderate visual field defects (24-2 standard mean deviations better than the Swedish interactive thresholding algorithm standard of 12 dB)

• No adequate IOP control (low treatment compliance, substantial adverse effects with eyedrops, and at least 2 IOP measurements higher than the individualized target IOP)

Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Other Locations
Canada
Eye Care Centre, Victoria General Hospital
RECRUITING
Halifax
Contact Information
Primary
Rami Darwich, MD, PhD
Darwich.Rami@mayo.edu
507-284-2787
Time Frame
Start Date: 2025-01-06
Estimated Completion Date: 2025-12-17
Participants
Target number of participants: 102
Treatments
Experimental: Nasal 180° Selective Laser Trabeculoplasty (SLT)
The Nasal 180° Selective Laser Trabeculoplasty (SLT) will be performed on the right eye.~After 90 days, the Inferior 180° Selective Laser Trabeculoplasty (SLT) will be performed on the right eye.
Experimental: Inferior 180° Selective Laser Trabeculoplasty (SLT)
The Inferior 180° Selective Laser Trabeculoplasty (SLT) will be performed on the right eye.~After 90 days, the Nasal 180° Selective Laser Trabeculoplasty (SLT) will be performed on the right eye.
Sponsors
Leads: Mayo Clinic

This content was sourced from clinicaltrials.gov